An enclosure or plenum that supports a looped pump tube is hingedly connected to a framed thin-walled heat exchange bag through which working fluid from an intravascular heat exchange catheter flows. The frame with bag can be inserted between cold plates to exchange heat with the working fluid flowing through the bag. With the framed bag between the plates, the looped pump tube from the enclosure or plenum is receivable in the raceway of a peristaltic pump, which pumps working fluid through the system.