Provided is a method for generating a preamble of a transmission signal for human body communication, the method including using a frequency shift code (FSC) of which a length is adjusted according to an operating clock frequency or a transmission rate and a first pseudo random binary sequence (PRBS) code of p chips where p is a natural number to generate a first preamble unit block of n chips where n is a natural number, using the FSC and a second PRBS code of p′ chips to generate a second preamble unit block of n′ chips, and arraying the first preamble unit block consecutively and repeatedly and disposing the second preamble unit block at a next stage to form the preamble of the transmission signal.