A synchronization controller for a multi-sensor camera device includes a detection circuit and a control circuit. The detection circuit detects asynchronization between image outputs generated from the multi-sensor camera device, wherein the image outputs correspond to different viewing angles. The control circuit controls an operation of the multi-sensor camera device in response to the asynchronization detected by the detection circuit. In addition, a synchronization method applied to a multi-sensor camera device includes following steps: detecting asynchronization between image outputs generated from the multi-sensor camera device, wherein the image outputs correspond to different viewing angles; and controlling an operation of the multi-sensor camera device in response to the detected asynchronization.