An inkjet printing system includes a fluid coupling assembly for supplying fluid to a jetting module. The jetting module includes an electrical connector adapted to connect with a corresponding electrical cable, and a jetting module attachment face with a jetting module fluid port. The fluid coupling assembly includes a coupling assembly attachment face with a coupling assembly fluid port in a position corresponding to the jetting module fluid port. A latch mechanism on the fluid coupling assembly includes a latch handle and a latch fastener adapted to engage with a latch keeper on the jetting module. When the latch handle is in a first disengaged position the latch mechanism blocks the electrical connector, and when the latch handle is in a second engaged position the latch fastener engages the latch keeper to secure the fluid coupling assembly to the jetting module.