- 专利标题： Pyrazolo compounds and uses thereof
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申请号： US14775405申请日： 2014-03-13
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公开(公告)号： US10035801B2公开(公告)日： 2018-07-31
- 发明人: Brian K. Albrecht , Steven F. Bellon , Victor S. Gehling , Jean-Christophe Harmange , Kwong Wah Lai , Jun Liang , Peter Dragovich , Daniel F. Ortwine , Sharada Labadie , Birong Zhang , James Richard Kiefer
- 申请人： CONSTELLATION PHARMACEUTICALS, INC. , GENENTECH, INC.
- 申请人地址： US CA South San Francisco US MA Cambridge
- 专利权人： GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS INC.
- 当前专利权人： GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS INC.
- 当前专利权人地址： US CA South San Francisco US MA Cambridge
- 代理机构： Viksnins Harris Padys Malen LLP
- 国际申请： PCT/CN2014/000262 WO 20140313
- 国际公布： WO2014/139326 WO 20140918
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A61K45/06 ; A61K31/5377 ; A61K31/337 ; A61K31/517 ; A61K31/437 ; C12N9/99 ; C07D498/04 ; C07D487/14
摘要：
Provided are compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using the present composition in the treatment of various disorders.
公开/授权文献
- US20160060267A1 PYRAZOLO COMPOUNDS AND USES THEREOF 公开/授权日：2016-03-03
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