A method (200) of bias cancellation for a radio channel sequence includes: receiving (201) a radio signal, the radio signal comprising a radio channel sequence coded by a first signature, the first signature belonging to a set of orthogonal signatures; decoding (202) the radio channel sequence based on the first signature to generate a decoded radio channel sequence; decoding (203) the radio channel sequence based on a second signature, wherein the second signature is orthogonal to the signatures of the set of orthogonal signatures, to generate a bias of the radio channel sequence; and canceling (204) the bias of the radio channel sequence from the decoded radio channel sequence.