- 专利标题: Metal complex catalyst, preparation method thereof, and use thereof in preparing D,L-menthol
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申请号: US15565593申请日: 2016-05-10
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公开(公告)号: US10058849B2公开(公告)日: 2018-08-28
- 发明人: Ming Yu , Jintao Yuan , Haidong Yu , Weikang Shao , Yuhong Zhang
- 申请人: ZHEJIANG NHU COMPANY LTD. , ZHEJIANG UNIVERSITY , SHANDONG NHU PHARMACEUTICAL CO., LTD.
- 申请人地址: CN Shaoxing CN Hangzhou CN Weifang
- 专利权人: ZHEJIANG NHU COMPANY LTD.,ZHEJIANG UNIVERSITY,SHANDONG NHU PHARMACEUTICAL CO., LTD.
- 当前专利权人: ZHEJIANG NHU COMPANY LTD.,ZHEJIANG UNIVERSITY,SHANDONG NHU PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: CN Shaoxing CN Hangzhou CN Weifang
- 代理商 Jiwen Chen
- 优先权: CN201510264486 20150521
- 国际申请: PCT/CN2016/081518 WO 20160510
- 国际公布: WO2016/184328 WO 20161124
- 主分类号: B01J23/847
- IPC分类号: B01J23/847 ; C07C35/12 ; C07C29/20 ; C07C29/56
摘要:
The present invention discloses a metal complex catalyst, its preparing method and its application in preparing D,L-menthol, the metal complex catalyst includes weight percent elements as follows: 70-85% of Ni, 8-10% of Al, 5-10% of V, and 2-10% of Co. When this metal complex catalyst is applied in preparing D,L-menthol through thymol hydrogenation, it has the characteristics of high reaction activity and quick racemization of chiral compound. Meanwhile, a certain kind of alkali added in isomerization is the key to reducing light constituent byproduct. The whole process comes in good reaction selectivity, simple preparing technology, low production cost, and environment-friendly synthetic route.