- 专利标题: Ionic liquid supported synthesis
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申请号: US11908487申请日: 2006-03-15
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公开(公告)号: US10059736B2公开(公告)日: 2018-08-28
- 发明人: Tak-Hang Chan , Masad J. Damha , Weishi Miao , Robert Alexander Donga , Xun He
- 申请人: Tak-Hang Chan , Masad J. Damha , Weishi Miao , Robert Alexander Donga , Xun He
- 申请人地址: CA Montreal
- 专利权人: McGill University
- 当前专利权人: McGill University
- 当前专利权人地址: CA Montreal
- 代理机构: DLA Piper LLP (US)
- 国际申请: PCT/CA2006/000355 WO 20060315
- 国际公布: WO2006/096963 WO 20060921
- 主分类号: C07H21/00
- IPC分类号: C07H21/00 ; C07H3/06 ; C07K1/02 ; C07K1/04
摘要:
The present invention relates to ionic liquids for use in chemical applications and capable of serving the dual function of solvent and liquid support. The ionic liquid lends itself to a method of synthesizing oligomers selected from the group consisting of oligopeptides, oligosaccharides and oligonucleotides, comprising contacting a first monomer unit with an ionic liquid at reaction conditions to provide an ionic liquid bound monomer unit; and contacting the ionic liquid bound monomer unit with at least one further monomer unit at reaction conditions to provide an ionic liquid bound oligomer comprising from 2 to 30 monomer units. The method lends itself to large scale manufacture of oligopeptides, oligosaccharides and oligonucleotides.
公开/授权文献
- US20100041869A1 IONIC LIQUID SUPPORTED SYNTHESIS 公开/授权日:2010-02-18
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