Invention Grant
- Patent Title: Combination therapy using c-Met inhibitor and IGF-1R inhibitor for c-Met inhibitor resistant cancers
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Application No.: US14949041Application Date: 2015-11-23
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Publication No.: US10064939B2Publication Date: 2018-09-04
- Inventor: Seon Hui Shim , Ji Min Lee , Soo Yeon Jung , Woo Sun Kwon , Kyung Ah Kim , Jeong Min Kim , Sun Young Rha , Won Suk Lee
- Applicant: Samsung Electronics Co., Ltd. , Yonsei University, University-Industry Foundation (UIF)
- Applicant Address: KR Suwon-si KR Seoul
- Assignee: SAMSUNG ELECTRONICS CO., LTD.,YONSEI UNIVERSITY, UNIVERSITY-INDUSTRY FOUNDATION (UIF)
- Current Assignee: SAMSUNG ELECTRONICS CO., LTD.,YONSEI UNIVERSITY, UNIVERSITY-INDUSTRY FOUNDATION (UIF)
- Current Assignee Address: KR Suwon-si KR Seoul
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: KR10-2014-0163792 20141121
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/00 ; C07K16/28 ; A61K31/4985 ; G01N33/574 ; G01N33/74 ; A61K39/00
Abstract:
A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met (hereinafter, ‘c-Met inhibitor’) and an IGF-1R inhibitor to a subject in need thereof and a use of IGF-1R as a marker for resistance to a c-Met inhibitor.
Public/Granted literature
- US20160144027A1 COMBINATION THERAPY USING C-MET INHIBITOR AND IGF-1R INHIBITOR Public/Granted day:2016-05-26
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