- 专利标题： Pharmaceutical formulations of TNF-alpha antibodies
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申请号： US14383533申请日： 2013-03-05
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公开(公告)号： US10093728B2公开(公告)日： 2018-10-09
- 发明人: Sanjeev Kumar Mendiratta , Sanjay Bandyopadhyay , Chintan G. Patel
- 申请人： Cadila Healthcare Limited
- 申请人地址： IN Ahmedabad
- 专利权人： CADILA HEALTHCARE LIMITED
- 当前专利权人： CADILA HEALTHCARE LIMITED
- 当前专利权人地址： IN Ahmedabad
- 代理机构： Goodwin Procter LLP
- 优先权： IN610/MUM/2012 20120307; IN1606/MUM/2012 20120530; IN3031/MUM/2012 20121017
- 国际申请： PCT/IN2013/000129 WO 20130305
- 国际公布： WO2013/164837 WO 20131107
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; A61K39/395 ; A61K9/19 ; A61K47/18 ; A61K47/26
摘要：
The present invention provides certain improved formulations of proteins. Specifically, the present invention provides use of certain excipients that are useful for stabilization of antibody preparations. Additionally, the novel formulations of the present invention prevents the formation of aggregates or fragments or modifications of protein in solution.
公开/授权文献
- US20150071936A1 PHARMACEUTICAL FORMULATIONS OF TNF-ALPHA ANTIBODIES 公开/授权日：2015-03-12
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