Invention Grant
- Patent Title: Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms
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Application No.: US14456268Application Date: 2014-08-11
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Publication No.: US10093978B2Publication Date: 2018-10-09
- Inventor: Brian Yaspan , Robert Royal Graham , Amy Dressen , Zhengrong Li , Erich Strauss , Teodorica Bugawan
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Jones Day
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883 ; C07K16/40 ; A61K39/00
Abstract:
The invention provides methods and compositions for treating various degenerative diseases (e.g., AMD) with a factor D inhibitor (e.g., anti-factor D antibody or antigen-binding fragment thereof). Also provided are methods of selecting or identifying patients for treatment with a factor D inhibitor. Methods include the use of prognostic and/or predictive biomarkers.
Public/Granted literature
- US20150044205A1 COMPOSITIONS AND METHOD FOR TREATING COMPLIMENT-ASSOCIATED CONDITIONS Public/Granted day:2015-02-12
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