Invention Grant
![N-[2-(2-amino-6,6-disubstituted-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-YL)-1,3-thiazol-4-YL] amides](/docs/US/2018-10-30/US10112958B2/abs.jpg.600x600.jpg)
- Patent Title: N-[2-(2-amino-6,6-disubstituted-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-YL)-1,3-thiazol-4-YL] amides
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Application No.: US15646572Application Date: 2017-07-11
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Publication No.: US10112958B2Publication Date: 2018-10-30
- Inventor: Michael Aaron Brodney , Christopher Ryan Butler , Lei Zhang , Brian Thomas O'Neill , Patrick Robert Verhoest , Peter Justin Mikochik , John Charles Murray , Xinjun Hou
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Lisa A. Samuels
- Main IPC: C07D513/04
- IPC: C07D513/04 ; C07D513/10 ; C07D513/20
![N-[2-(2-amino-6,6-disubstituted-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-YL)-1,3-thiazol-4-YL] amides](/abs-image/US/2018/10/30/US10112958B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, and the variables R1, R2 and R3 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
Public/Granted literature
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