Techniques are disclosed relating to managing data-request dependencies for a cache. In one embodiment, an integrated circuit is disclosed that includes a plurality of requesting agents and a cache. The cache is configured to receive read and write requests from the plurality of requesting agents including a first request and a second request. The cache is configured to detect that the first and second requests specify addresses that correspond to different portions of the same cache line, and to determine whether to delay processing one of the first and second requests based on whether the first and second requests are from the same requesting agent. In some embodiments, the cache is configured to service the first and second requests in parallel in response to determining that the first and second requests are from the same requesting agent.