- 专利标题： Piperazine derivatives as liver X receptor modulators
-
申请号： US15502356申请日： 2015-08-04
-
公开(公告)号： US10144715B2公开(公告)日： 2018-12-04
- 发明人: David A. Claremon , Chengguo Dong , Yi Fan , Katerina Leftheris , Stephen D. Lotesta , Suresh B. Singh , Colin M. Tice , Wei Zhao , Yajun Zheng , Linghang Zhuang
- 申请人： Vitae Pharmaceuticals, Inc.
- 申请人地址： US NJ Madison
- 专利权人： Vitae Pharmaceuticals, Inc.
- 当前专利权人： Vitae Pharmaceuticals, Inc.
- 当前专利权人地址： US NJ Madison
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Michael J. DeGrazia
- 国际申请： PCT/US2015/043538 WO 20150804
- 国际公布： WO2016/022521 WO 20160211
- 主分类号： C07D241/04
- IPC分类号： C07D241/04 ; C07D403/04 ; C07D413/14 ; C07D401/04 ; C07D401/06 ; C07D403/14 ; C07D405/06 ; C07D413/04 ; C07D417/04 ; C07D417/14 ; C07D497/04 ; C07D513/04
摘要：
Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.
公开/授权文献
- US20170226067A1 PIPERAZINE DERIVATIVES AS LIVER X RECEPTOR MODULATORS 公开/授权日：2017-08-10
信息查询
