Invention Grant
- Patent Title: Anthracycline disulfide intermediates, antibody-drug conjugates and methods
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Application No.: US14851206Application Date: 2015-09-11
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Publication No.: US10149913B2Publication Date: 2018-12-11
- Inventor: John A. Flygare , Thomas H. Pillow
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Viksnins Harris Padys Malen LLP
- Main IPC: A61K47/68
- IPC: A61K47/68 ; A61K47/48 ; A61K31/704
Abstract:
The invention provides antibody-drug conjugates comprising an antibody conjugated to an anthracycline drug moiety via a disulfide linker, anthracycline disulfide intermediates, and methods of using the antibody-drug conjugates.
Public/Granted literature
- US20160074528A1 ANTHRACYCLINE DISULFIDE INTERMEDIATES, ANTIBODY-DRUG CONJUGATES AND METHODS Public/Granted day:2016-03-17
Information query
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