- 专利标题： Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells
-
申请号： US15107889申请日： 2013-10-28
-
公开(公告)号： US10155780B2公开(公告)日： 2018-12-18
- 发明人: Gulilat Gebeyehu , Joel Jessee
- 申请人： MOLECULAR TRANSFER, INC.
- 申请人地址： US MD Gaithersburg
- 专利权人： MOLECULAR TRANSFER, INC.
- 当前专利权人： MOLECULAR TRANSFER, INC.
- 当前专利权人地址： US MD Gaithersburg
- 代理机构： TechLaw LLP
- 代理商 Sam K. Tahmassebi
- 国际申请： PCT/US2013/067157 WO 20131028
- 国际公布： WO2014/070687 WO 20140508
- 主分类号： C07F9/10
- IPC分类号： C07F9/10 ; C12N15/113 ; C12N15/88 ; C12P21/00 ; C07F9/6506
摘要：
New cationic lipids are provided that are useful for delivering macromolecules, such as nucleic acids, into eukaryotic cells. The lipids can be used alone, in combination with other lipids and/or in combination with other transfection enhancing reagents to prepare transfection complexes. The present invention is in the field of molecular biology, and more particularly in the field of transfection, which utilizes new compounds and methods for the introduction of nucleic acids into eukaryotic cells.
公开/授权文献
信息查询
