发明授权
- 专利标题: Stable liquid filled hard capsule comprising beta-hydroxy-beta methylbutyric acid
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申请号: US15036162申请日: 2014-12-11
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公开(公告)号: US10188611B2公开(公告)日: 2019-01-29
- 发明人: Tyler Oswald White
- 申请人: Capsugel Belgium NV
- 申请人地址: BE Bornem
- 专利权人: Capsugel Belguim NV
- 当前专利权人: Capsugel Belguim NV
- 当前专利权人地址: BE Bornem
- 代理机构: Klarquist Sparkman, LLP
- 国际申请: PCT/US2014/069831 WO 20141211
- 国际公布: WO2015/094925 WO 20150625
- 主分类号: A61K9/48
- IPC分类号: A61K9/48 ; A61K31/19
摘要:
The present disclosure relates to liquid filled hard capsules comprising hydroxypropyl methyl cellulose, pullulan, or mixtures thereof comprising a liquid fill of an effective amount of beta-hydroxy-beta-methylbutyric acid (HMB free acid) in liquid form and at least on excipient selected from quaternary ammonium salts, amino acids, amino acid derivatives, monosaccharides, disaccharides, and mixtures thereof.
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