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公开(公告)号：US20240115499A1
公开(公告)日：2024-04-11
申请号：US17769038
申请日：2020-10-15
申请人： Capsugel Belgium NV
发明人： Tyler Oswald White , Kelli Fowler
CPC分类号： A61K9/107 , A61K9/4808 , A61K9/4858 , A61K9/4866 , A61K31/14
摘要： The present disclosure is directed to an oil-in-water emulsion containing at least one hygroscopic ingredient and an edible oil. The emulsion has a water activity of less than about 0.6. The emulsion may be incorporated into an oral dosage form, including a capsule oral dosage form. The ingredients provided in the emulsion are capable of improving the health or well-being of a human or animal.
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公开(公告)号：US11925954B2
公开(公告)日：2024-03-12
申请号：US17775008
申请日：2020-11-05
申请人： Capsugel Belgium NV
发明人： Cody Prather , Randy Ham , John Dugan
摘要： A nozzle assembly includes a nozzle, a manifold, and wand body. The nozzle, manifold, and wand body can be coupled together to provide a robust spray drying system that can withstand elevated temperature and/or pressure feed stock. In some embodiments, an internal shoulder portion of the manifold can engage with a side of a nozzle collar to restrict distal movement of the nozzle relative to the manifold.
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3.发明公开公开(公告)号：US20240058225A1
公开(公告)日：2024-02-22
申请号：US18371163
申请日：2023-09-21
申请人： Capsugel Belgium NV
发明人： Kaori Sato , Takahisa Takubo , Hitomi Doi
CPC分类号： A61K8/0204 , A61K8/11 , A61K8/37 , A61K8/46 , A61K8/65 , A61K8/731 , A61K8/86 , A61K2800/10 , A61K2800/26 , A61K2800/43 , A61K2800/594 , A61K2800/92
摘要： [Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide.
[Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.-
公开(公告)号：US20230172246A1
公开(公告)日：2023-06-08
申请号：US18014005
申请日：2021-06-30
申请人： Capsugel Belgium NV
发明人： Tyler White , Kelli Fowler , Aouatef Bellamine
IPC分类号： A23L33/105 , A23L33/115 , A23L33/24 , A23L33/00
CPC分类号： A23L33/105 , A23L33/115 , A23L33/24 , A23L33/30
摘要： A composition, such as a dietary composition is disclosed containing one or more capsaicinoids contained within a lipid matrix. In one embodiment, the composition contains a liquid capsaicin in addition to a capsaicin wax. The composition is formulated such that when is ingested does not break down in the stomach but instead releases the capsaicin in the small intestines for various dietary benefits, including appetite suppression.
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公开(公告)号：US20230090812A1
公开(公告)日：2023-03-23
申请号：US17978780
申请日：2022-11-01
申请人： Capsugel Belgium NV
IPC分类号： A61K9/48
摘要： The present invention provides ingestible dosage form articles such as opaque capsules with reduced light transmittance.
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公开(公告)号：US20220370392A1
公开(公告)日：2022-11-24
申请号：US17765156
申请日：2020-10-16
发明人： Aouatef Bellamine , Stanislaw Glab , Shane Durkee
IPC分类号： A61K31/205 , A61K9/16 , A61K45/06 , A61K9/48 , A61P21/06
摘要： A method and composition for increasing muscle protein synthesis in mammals is disclosed. In one embodiment, the mammals are administered a protein building composition comprising at an amino acid component including L-carnitine and a nitrogenous organic acid including creatine. In a particular embodiment, the creatine is in a solution with L-carnitine. The ratio of L-carnitine to creatine can be from about 10:1 to about 1:1. The protein building z composition can be administered in a monolithic enteric capsule.
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公开(公告)号：US20220361552A1
公开(公告)日：2022-11-17
申请号：US17784315
申请日：2020-12-10
申请人： Tyler WHITE , Capsugel Belgium NV
发明人： Tyler White , Christopher Craig , David Vodak , Shane Durkee
IPC分类号： A23P10/35 , A23L33/155 , A23L33/105 , A61K31/01 , A61K31/07 , A61K31/122 , A61K9/48 , A61K9/50
摘要： A composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein is disclosed. The active ingredient can include a fat-soluble active ingredient. The particles can be contained in a capsule. Also provided are methods for producing a pharmaceutical composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein.
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公开(公告)号：US20220347106A1
公开(公告)日：2022-11-03
申请号：US17761296
申请日：2020-10-08
申请人： CAPSUGEL BELGIUM NV
摘要： The invention discloses opaque capsule shells made from gelatin with ground CaCO3 as opacifier; and a method for making them.
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公开(公告)号：US20210220285A1
公开(公告)日：2021-07-22
申请号：US17224550
申请日：2021-04-07
申请人： Capsugel Belgium NV
发明人： Xiongwei David He , Stefaan Jaak Vanquickenborne , Jonathan Leonard Cape , Dwayne Thomas Friesen
摘要： An acid resistant capsule comprises at least one hard capsule shell, said shell comprising: an enteric polymer having acid groups; a film-forming aid; and an alkaline material, wherein said alkaline material is present in an amount such that said carboxylic acid groups of said enteric polymer have a degree of ionization of less than 15%.
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公开(公告)号：US20210052505A1
公开(公告)日：2021-02-25
申请号：US17046132
申请日：2019-05-14
申请人： Capsugel Belgium NV
IPC分类号： A61K9/48
摘要： The present invention provides ingestible dosage form articles such as opaque capsules with reduced light transmittance.
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