Invention Grant
- Patent Title: Compositions and methods for treating insomnia
-
Application No.: US15519676Application Date: 2015-10-21
-
Publication No.: US10188652B2Publication Date: 2019-01-29
- Inventor: Margaret Moline , Gina Pastino , Yurie Akimoto , Yasuhiro Zaima , Nobuya Suzuki , Nobuo Yoshida
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- International Application: PCT/JP2015/080304 WO 20151021
- International Announcement: WO2016/063995 WO 20160428
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K9/00 ; A61K9/20 ; A61K9/48
Abstract:
In the present invention, compound such as (1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl) cyclopropanecarboxamide have been found to be potent orexin receptor antagonists, and may be useful in the treatment of sleep disorders such as insomnia, as well as for other therapeutic uses.
Public/Granted literature
- US20170252342A1 COMPOSITIONS AND METHODS FOR TREATING INSOMNIA Public/Granted day:2017-09-07
Information query
IPC分类:
