- 专利标题: Method for producing orodispersible tablets
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申请号: US14125240申请日: 2012-06-08
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公开(公告)号: US10195154B2公开(公告)日: 2019-02-05
- 发明人: Yohei Hoashi , Naohisa Katayama , Shunsuke Daidouji
- 申请人: Yohei Hoashi , Naohisa Katayama , Shunsuke Daidouji
- 申请人地址: JP Osaka-shi
- 专利权人: Nipro Corporation
- 当前专利权人: Nipro Corporation
- 当前专利权人地址: JP Osaka-shi
- 代理机构: The Webb Law Firm
- 优先权: JP2011-129812 20110610
- 国际申请: PCT/JP2012/064788 WO 20120608
- 国际公布: WO2012/169614 WO 20121213
- 主分类号: A61K9/28
- IPC分类号: A61K9/28 ; A61K9/00 ; A61K9/20 ; A61K9/50 ; A61K31/00 ; A61K31/196 ; A61K31/4178
摘要:
A method for easily producing orodispersible tablets that secure an eluting behavior of a principal agent in the digestive tract and mask unpleasant taste in the oral cavity is provided. Provided is a method for producing orodispersible tablets which includes mixing an additive to a principal agent to form principal agent particles as a granulation process, coating the principal agent particles with a coating agent to form coated particles as a coating process, and tableting the coated particles to form tablets as a tableting process, wherein the additive used in the granulation process contains a pH regulator, and the coating agent used in the coating process contains a pH-dependent polymer dissolving at pH 5 or more.
公开/授权文献
- US20140093567A1 Method for Producing Orodispersible Tablets 公开/授权日:2014-04-03
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