Invention Grant
- Patent Title: Methods of detecting target nucleic acids
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Application No.: US15614606Application Date: 2017-06-05
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Publication No.: US10196680B2Publication Date: 2019-02-05
- Inventor: Muhammad A. Sharaf , Timothy Woudenberg , Khairuzzaman Bashar Mullah
- Applicant: APPLIED BIOSYSTEMS, LLC
- Applicant Address: US CA Carlsbad
- Assignee: APPLIED BIOSYSTEMS, LLC
- Current Assignee: APPLIED BIOSYSTEMS, LLC
- Current Assignee Address: US CA Carlsbad
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6825 ; C12Q1/6816 ; C12Q1/6876 ; C12Q1/6823 ; C12Q1/6827 ; C12Q1/6832 ; G01N27/447

Abstract:
The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
Public/Granted literature
- US20170275678A1 METHODS OF DETECTING TARGET NUCLEIC ACIDS Public/Granted day:2017-09-28
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