Invention Grant
- Patent Title: Nitrogen-containing heterocyclic compound
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Application No.: US15311025Application Date: 2015-05-15
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Publication No.: US10208046B2Publication Date: 2019-02-19
- Inventor: Takahiro Sugimoto , Kenichiro Shimokawa , Takuto Kojima , Hiroki Sakamoto , Ikuo Fujimori , Minoru Nakamura , Masami Yamada , Masataka Murakami , Makoto Kamata , Shinkichi Suzuki
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2014-102322 20140516
- International Application: PCT/JP2015/064113 WO 20150515
- International Announcement: WO2015/174534 WO 20151119
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D487/04 ; A61K31/444 ; A61K31/4545 ; A61K31/501 ; A61K31/519 ; C07D471/04

Abstract:
The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity, which may be useful as medicaments such as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies and the like, and the like. The present invention relates to a compound represented by the formula (I) wherein ring A is an optionally substituted 5- or 6-membered ring; R is a C1-6 alkyl group substituted by 1 to 5 halogen atoms; and X is —CH═ or —N═, or a salt thereof.
Public/Granted literature
- US20170081332A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND Public/Granted day:2017-03-23
Information query
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