A system for use in a well includes a completion system having a shoulder contact region, an electric submersible pumping system deployed downhole via a cable for landing on the completion system, a tubular member coupled to the electric submersible pumping system and extending downhole from the electric submersible pumping system, and a shoulder mechanism slidably mounted on the tubular member for engagement with the shoulder contact region during landing, the shoulder mechanism being selectively settable along the tubular member to counter tensile loading in the cable. The shoulder mechanism is set against the tubular member via anchors actuated against the tubular member, and the anchors are actuated by a piston movably mounted within a housing of the shoulder mechanism.