Invention Grant
- Patent Title: Nanopore-based sequencing with varying voltage stimulus
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Application No.: US15371106Application Date: 2016-12-06
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Publication No.: US10215731B2Publication Date: 2019-02-26
- Inventor: Roger J. A. Chen , Hui Tian , J. William Maney, Jr.
- Applicant: Genia Technologies, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: Genia Technologies, Inc.
- Current Assignee: Genia Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Van Pelt, Yi & James LLP
- Main IPC: G01N27/447
- IPC: G01N27/447 ; B01L3/00 ; C12Q1/6869 ; G01N33/487

Abstract:
A method of analyzing a molecule in a nanopore is disclosed. A voltage is applied across a nanopore that is inserted in a membrane by coupling the nanopore to a voltage source. The nanopore is decoupled from the voltage source. After the decoupling, a rate of decay of the voltage across the nanopore is determined. A molecule in the nanopore is distinguished from other possible molecules based on the determined rate of decay of the voltage across the nanopore.
Public/Granted literature
- US20170199150A1 NANOPORE-BASED SEQUENCING WITH VARYING VOLTAGE STIMULUS Public/Granted day:2017-07-13
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