The present invention relates to a method for efficient transmission of a request frame such as an RTS/CTS frame and a response frame in response to the request frame in a multi-user based wireless communication system. The method of the present invention comprises: a process where wireless terminals transmit a response frame at their own response frame transmission time through a request frame that contains information about a plurality of wireless terminals and information about the response frame transmission time of the respective wireless terminals; a process where the respective wireless terminals transmit a response frame according to a token scheme such that the response frame is transmitted to a final access point; and a process where only a representative wireless terminal selected depending on a given wireless environment receives the response frame.