- 专利标题: Fused piperidine amides as modulators of ion channels
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申请号: US14903475申请日: 2014-07-08
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公开(公告)号: US10233191B2公开(公告)日: 2019-03-19
- 发明人: Michael Paul Deninno , Corey Anderson , Erica Lynn Conroy , Bryan A. Frieman , Peter Diederik Jan Grootenhuis , Sara Sabina Hadida-Ruah , Dennis James Hurley , Fabrice Jean Denis Pierre , Alina Silina , Johnny Uy , Jinglan Zhou
- 申请人: Vertex Pharmaceuticals Incorporated
- 申请人地址: US MA Boston
- 专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人地址: US MA Boston
- 代理机构: Brinks Gilson & Lione
- 国际申请: PCT/US2014/045675 WO 20140708
- 国际公布: WO2015/006280 WO 20150115
- 主分类号: C07D491/056
- IPC分类号: C07D491/056 ; C07D221/04 ; C07D401/06 ; C07D405/06 ; C07D405/12 ; C07D487/04 ; C07D491/044 ; C07D491/048 ; C07D401/04 ; C07D403/06
摘要:
The invention relates to fused piperidine amides useful as inhibitors of ion channels for the treatment of pain. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
公开/授权文献
- US20160159815A1 Fused Piperidine Amides as Modulators of Ion Channels 公开/授权日:2016-06-09
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