- 专利标题: Methods for in vitro memory B cell differentiation and transduction with VSV-G pseudotyped viral vectors
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申请号: US14776283申请日: 2014-03-14
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公开(公告)号: US10240125B2公开(公告)日: 2019-03-26
- 发明人: Mei Xu , Matthew Rein Scholz , Eric J. Herbig
- 申请人: Immusoft Corporation
- 申请人地址: US WA Seattle
- 专利权人: Immusoft Corporation
- 当前专利权人: Immusoft Corporation
- 当前专利权人地址: US WA Seattle
- 代理机构: Cooley LLP
- 国际申请: PCT/US2014/027910 WO 20140314
- 国际公布: WO2014/152832 WO 20140925
- 主分类号: C12N5/00
- IPC分类号: C12N5/00 ; C12N15/86 ; C12N5/0781 ; A61K48/00
摘要:
The present disclosure relates to the in vitro differentiation of memory B cells to plasmablasts or plasma cells and genetic modification of these cells to express a protein of interest, such as a specific antibody or other protein therapeutic.
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