A device and a method for supporting clock transfer of multiple clock domains, where the device includes N phase frequency detectors, N filters, N clock reconstructors, and N clock domain interfaces, where N is an integer greater than or equal to two, the N clock domain interfaces are in a one-to-one correspondence with the N phase frequency detectors, the N filters, and the N clock reconstructors, the N phase frequency detectors are respectively connected to N clock sources, and at least two clock sources of the N clock sources are different. The foregoing device flexibly adapt to multiple different clock domains, implement that a single device simultaneously supports clock transfer of multiple clock domains, and flexibly satisfy user demands without adding or replacing devices.