- Patent Title: Method and system for fragment assembly and sequence identification
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Application No.: US15811544Application Date: 2017-11-13
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Publication No.: US10255990B2Publication Date: 2019-04-09
- Inventor: Zachary Apte , Jessica Richman , Daniel Almonacid , Rodrigo Ortiz
- Applicant: uBiome, Inc.
- Applicant Address: US CA San Francisco
- Assignee: uBiome, Inc.
- Current Assignee: uBiome, Inc.
- Current Assignee Address: US CA San Francisco
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: G06F19/22
- IPC: G06F19/22 ; C12N15/10 ; C12Q1/6869 ; G16B30/00 ; C40B50/06

Abstract:
Embodiments of a method and/or system for improving fragment assembly and/or sequence identification includes: collecting a sample including a set of nucleic acid components associated with a set of microorganisms; generating a set of tagged sequence fragments; amplifying the set of tagged sequence fragments and sequencing the set of tagged sequence fragments; based upon the set of identifier tags, generating a set of branched assemblies of candidate sequence fragments, wherein each of the set of branched assemblies includes a set of ordered nodes and a set of branches distributed across the set of nodes; implementing a threshold criterion to reduce the set of branched assemblies to a set of branch-reduced assemblies; and identifying a set of sequences corresponding to the set of branch-reduced assemblies and/or generating an analysis informative of the set of microorganisms associated with the sample.
Public/Granted literature
- US20180137240A1 METHOD AND SYSTEM FOR FRAGMENT ASSEMBLY AND SEQUENCE IDENTIFICATION Public/Granted day:2018-05-17
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