Invention Grant
- Patent Title: Methods of generating glial and neuronal cells and use of same for the treatment of medical conditions of the CNS
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Application No.: US15468020Application Date: 2017-03-23
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Publication No.: US10258651B2Publication Date: 2019-04-16
- Inventor: Michel Revel , Judith Chebath , Michal Izrael , Rosalia Kaufman
- Applicant: Yeda Research and Development Co. Ltd.
- Applicant Address: IL Rechovot
- Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- Current Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- Current Assignee Address: IL Rechovot
- Agency: Polsinelli PC
- Agent Ron Galant
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K35/30 ; C12N5/0793 ; C12N5/079 ; G01N33/50
Abstract:
A method of generating neural and glial cells is provided. The method comprising growing human stem cells under conditions which induce differentiation of said human stem cells into the neural and glial cells, said conditions comprising the presence of retinoic acid and an agent capable of down-regulating Bone Morphogenic Protein activity.
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