- 专利标题： Use of PAR-1 antagonists for preventing and/or treating pelvi-perineal functional pathological conditions
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申请号： US15962837申请日： 2018-04-25
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公开(公告)号： US10265322B2公开(公告)日： 2019-04-23
- 发明人: Bruno Le Grand , Didier Junquero , Nicolas Monjotin
- 申请人： PIERRE FABRE MEDICAMENT
- 申请人地址： FR Boulogne-Billancourt
- 专利权人： Pierre Fabre Medicament
- 当前专利权人： Pierre Fabre Medicament
- 当前专利权人地址： FR Boulogne-Billancourt
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： FR1362682 20131216
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; A61K31/5377 ; A61K31/443 ; A61P13/10 ; A61P13/00
摘要：
The present invention relates to the use of PAR1 antagonists, in particular of vorapaxar, of atopaxar and of 3-(2-chlorophenyl)-1-[4-(4-fluorobenzyl)piperazin-1-yl]propenone, or a pharmaceutically acceptable salt thereof, for preventing and/or treating pelvi-perineal functional pathological conditions, and more particularly painful bladder syndrome.