公开(公告)号：US10265322B2

公开(公告)日：2019-04-23

申请号：US15962837

申请日：2018-04-25

申请人： PIERRE FABRE MEDICAMENT

发明人： Bruno Le Grand ,  Didier Junquero ,  Nicolas Monjotin

IPC分类号： A61K31/495 ,  A61K31/5377 ,  A61K31/443 ,  A61P13/10 ,  A61P13/00

摘要： The present invention relates to the use of PAR1 antagonists, in particular of vorapaxar, of atopaxar and of 3-(2-chlorophenyl)-1-[4-(4-fluorobenzyl)piperazin-1-yl]propenone, or a pharmaceutically acceptable salt thereof, for preventing and/or treating pelvi-perineal functional pathological conditions, and more particularly painful bladder syndrome.

公开(公告)号：US09980970B2

公开(公告)日：2018-05-29

申请号：US15101170

申请日：2014-10-31

申请人： PIERRE FABRE MEDICAMENT

发明人： Bruno Le Grand ,  Didier Junquero ,  Nicolas Monjotin

IPC分类号： A61K31/5377 ,  A61K31/495 ,  A61K31/443

CPC分类号： A61K31/5377 ,  A61K31/443 ,  A61K31/495

摘要： The present invention relates to the use of PAR1 antagonists, in particular of vorapaxar, of atopaxar and of 3-(2-chlorophenyl)-1-[4-(4-fluorobenzyl)piperazin-1-yl]propenone, or a pharmaceutically acceptable salt thereof, for preventing and/or treating pelvi-perineal functional pathological conditions, and more particularly painful bladder syndrome.