- 专利标题： Linear peptides that mimic structural epitopes for antibody assays
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申请号： US14159308申请日： 2014-01-20
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公开(公告)号： US10267788B1公开(公告)日： 2019-04-23
- 发明人: Joseph S. Schoeniger , Peter Anderson
- 申请人： National Technology & Engineering Solutions of Sandia, LLC
- 申请人地址： US NM Albuquerque
- 专利权人： National Technology & Engineering Solutions of Sandia, LLC
- 当前专利权人： National Technology & Engineering Solutions of Sandia, LLC
- 当前专利权人地址： US NM Albuquerque
- 代理商 Madelynne J. Farber
- 主分类号： G01N33/531
- IPC分类号： G01N33/531 ; C07K14/005
摘要：
A method including identifying one or more structures in adjacent sequences of one or more proteins that can be mimicked by a peptide; and assembling a peptide that mimics the one or more secondary structures. A method including assembling epitopes of linked pairs of discontiguous peptide subsequences that mimic one or more structures in sequences of a protein; and assaying antibodies against the epitopes.
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