Invention Grant
- Patent Title: Modified bat influenza viruses and their uses
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Application No.: US15508670Application Date: 2015-09-04
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Publication No.: US10272149B2Publication Date: 2019-04-30
- Inventor: David Wentworth , Bin Zhou , Wenjun Ma , Jingjiao Ma
- Applicant: Kansas State University Research Foundation , David Wentworth , Bin Zhou
- Applicant Address: US KS Manhattan US MD Rockville
- Assignee: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION,J. CRAIG VENTER INSTITUTE
- Current Assignee: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION,J. CRAIG VENTER INSTITUTE
- Current Assignee Address: US KS Manhattan US MD Rockville
- Agency: Hovey Williams LLP
- International Application: PCT/US2015/048648 WO 20150904
- International Announcement: WO2016/037113 WO 20160310
- Main IPC: A61K39/145
- IPC: A61K39/145 ; G01N30/02 ; C12N15/09 ; A61K39/12 ; A61K39/00

Abstract:
Vaccine compositions useful for vaccination against a target influenza strain, and method and kits for using the same. The vaccines comprise a live attenuated influenza virus that is synthetically constructed based upon a backbone platform derived from a bat influenza strain, and heterologous surface proteins HA and NA derived from the target influenza strain. The live attenuated virus is non-reassortant with native, circulating influenza strains, and can be used to create vaccines for humans and other animals.
Public/Granted literature
- US20170274064A1 MODIFIED BAT INFLUENZA VIRUSES AND THEIR USES Public/Granted day:2017-09-28
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