- 专利标题： Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them
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申请号： US15492306申请日： 2017-04-20
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公开(公告)号： US10278972B2公开(公告)日： 2019-05-07
- 发明人: András Kotschy , Zoltán Szlávik , Márton Csékei , Attila Paczal , Zoltán Szabó , Szabolcs Sipos , Gábor Radics , Ágnes Proszenyák , Balázs Bálint , Alain Bruno , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , I-Jen Chen , Françoise Perron-Sierra
- 申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD
- 申请人地址： FR Suresnes GB Winnersh Berkshire
- 专利权人： LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人： LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人地址： FR Suresnes GB Winnersh Berkshire
- 代理机构： Hueschen and Sage
- 优先权： FR1363500 20131223
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D495/04 ; A61K31/5377 ; A61K31/538 ; A61K31/55 ; A61K45/06 ; A61N5/10
摘要：
Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R12, X, A and n are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
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