-
公开(公告)号：US10457689B2
公开(公告)日：2019-10-29
申请号：US16069891
申请日：2016-12-19
发明人： Attila Paczal , Zoltán Szlávik , András Kotschy , Maïa Chanrion , Ana Leticia Maragno , Olivier Geneste , Didier Demarles , Balázs Bálint , Szabolcs Sipos
IPC分类号： C07D495/04 , A61K31/519 , C07F9/6561 , A61P35/02 , A61K45/06
摘要： Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6 and Y are as defined in the description. Medicaments.
-
2.发明申请公开(公告)号：US20190248805A1
公开(公告)日：2019-08-15
申请号：US16394308
申请日：2019-04-25
发明人： Balázs Bálint , Márton Csékei , Zoltán Szabó , Zoltán Szlávik , András Kotschy , Maïa Chanrion , Olivier Geneste , I-Jen Chen , James Edward Paul Davidson , James Brooke Murray , Szabolcs Sipos , Levente Ondi , Ágnes Proszenyák
IPC分类号： C07D495/04 , C07D491/048 , C07D491/04 , C07D333/56 , A61P35/02 , C07D307/81 , C07D307/80 , C07D209/12 , C07D403/12 , C07D487/04 , C07D471/04 , C07D409/12 , C07D405/12 , C07D405/04
CPC分类号： C07D495/04 , A61K45/06 , A61K2300/00 , A61P35/02 , C07D209/12 , C07D307/80 , C07D307/81 , C07D333/56 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D491/048
摘要： Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A and n are as defined in the description.Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.
-
公开(公告)号：US10711010B2
公开(公告)日：2020-07-14
申请号：US16247614
申请日：2019-01-15
发明人： Zoltán Szlávik , András Kotschy , Maïa Chanrion , Didier Demarles , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , Szabolcs Sipos , Attila Paczal , Balázs Bálint
IPC分类号： A61P35/00 , A61K31/519 , A61K45/06 , C07D495/04
摘要： Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R13, Ra, Rb, A and n are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.
-
4.发明申请公开(公告)号：US20190201404A1
公开(公告)日：2019-07-04
申请号：US16296766
申请日：2019-03-08
发明人： András KOTSCHY , Zoltán Szlávik , Márton Csékei , Attila Paczal , Zoltán Szabó , Szabolcs Sipos , Gábor Radics , Ágnes Proszenyák , Balázs Bálint , Alain Bruno , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , I-Jen Chen , Françoise Perron-Sierra
IPC分类号： A61K31/519 , A61N5/10 , A61K45/06 , C07D495/04 , A61K31/538 , A61K31/5377 , A61K31/55
CPC分类号： A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K45/06 , A61N5/10 , C07D495/04
摘要： Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R12, X, A and n are as defined in the description.Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
-
公开(公告)号：US10457687B2
公开(公告)日：2019-10-29
申请号：US15737783
申请日：2016-06-22
发明人： Zoltán Szlávik , Zoltán Szabó , Márton Csékei , Attila Paczal , András Kotschy , Alain Bruno , Olivier Geneste , I-Jen Chen , James Edward Paul Davidson , James Brooke Murray , Levente Ondi , Gábor Radics , Szabolcs Sipos , Ágnes Proszenyák , Françoise Perron-Sierra , Balázs Bálint
IPC分类号： C07D495/04 , A61K31/519 , A61P37/00 , A61P35/00
摘要： Compounds of formula (I): wherein R1, R2, R5, R6, R7, R12, X, Y, A, E and n are as defined in the description. Medicinal products containing the same which are useful in treating a condition requiring a pro-apoptotic agent.
-
公开(公告)号：US10278972B2
公开(公告)日：2019-05-07
申请号：US15492306
申请日：2017-04-20
发明人： András Kotschy , Zoltán Szlávik , Márton Csékei , Attila Paczal , Zoltán Szabó , Szabolcs Sipos , Gábor Radics , Ágnes Proszenyák , Balázs Bálint , Alain Bruno , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , I-Jen Chen , Françoise Perron-Sierra
IPC分类号： A61K31/519 , C07D495/04 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K45/06 , A61N5/10
摘要： Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R12, X, A and n are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
-
公开(公告)号：US09670227B2
公开(公告)日：2017-06-06
申请号：US14576683
申请日：2014-12-19
发明人： András Kotschy , Zoltán Szlávik , Márton Csékei , Attila Paczal , Zoltán Szabó , Szabolcs Sipos , Gábor Radics , Ágnes Proszenyák , Balázs Bálint , Alain Bruno , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , I-Jen Chen , Françoise Perron-Sierra
IPC分类号： C07D239/00 , C07D333/00 , C07D495/04 , A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K45/06 , A61N5/10
CPC分类号： A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K45/06 , A61N5/10 , C07D495/04
摘要： Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R12, X, A and n are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
-
8.发明申请THIENOPYRIMIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 有权三硝基嘧啶衍生物及其制备方法及含有它们的药物组合物公开(公告)号：US20150175623A1
公开(公告)日：2015-06-25
申请号：US14576683
申请日：2014-12-19
发明人： András Kotschy , Zoltán Szlávik , Márton Csékei , Attila Paczal , Zoltán Szabó , Szabolcs Sipos , Gábor Radics , Ágnes Proszenyák , Balázs Bálint , Alain Bruno , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , I-Jen Chen , Françoise Perron-Sierra
IPC分类号： C07D495/04 , A61K45/06 , A61N5/10 , A61K31/55 , A61K31/538 , A61K31/519 , A61K31/5377
CPC分类号： A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K45/06 , A61N5/10 , C07D495/04
摘要： Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R12, X, A and n are as defined in the description.Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
摘要翻译： 式（I）化合物：其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 12，X，A和n如说明书中所定义。 含有该物质的药物可用于治疗涉及细胞凋亡缺陷的病症，如癌症，自身免疫疾病和免疫系统疾病。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.045 秒)
