- 专利标题： Method for detecting modulators of GPIb-thrombin interaction
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申请号： US14643938申请日： 2015-03-10
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公开(公告)号： US10281480B2公开(公告)日： 2019-05-07
- 发明人: Juergen Patzke
- 申请人： Siemens Healthcare Diagnostics Products GmbH
- 申请人地址： DE Marburg
- 专利权人： Siemens Healthcare Diagnostics Products GmbH
- 当前专利权人： Siemens Healthcare Diagnostics Products GmbH
- 当前专利权人地址： DE Marburg
- 代理机构： Dugan & Dugan, PC
- 优先权： EP14158716 20140311
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; G01N33/86
摘要：
The present invention is in the field of coagulation diagnostics and relates to methods for detecting modulators of GPIb-thrombin interaction in a sample. To this end, the sample is contacted with isolated mutated GPIbα protein and thrombin, and the formation of a complex between mutated GPIbα protein and thrombin is determined.
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