A method of dynamic spectrum sharing mechanism called listen-before-talk (LBT) is proposed for uplink transmission in Licensed Assisted Access (LAA). A maximum channel occupancy time (MCOT) including downlink (DL) transmission from one eNB and uplink (UL) transmission to the same eNB is introduced. A transmission sequence is defined as a number of subframes including possible partial subframes for DL and/or UL within a MCOT. The transmission in the first subframe among the transmission sequence is conducted after a Category 4 LBT. The transmission sequence within the MCOT can be initiated by either a DL transmission or an UL transmission. After the first subframe in a transmission sequence, LBT for another transmission is a fast DL LBT and/or fast UL LBT. Further, a Category 4 LBT can be converted to a short LBT (e.g., one shot CCA) for more efficient channel access.