Invention Grant
- Patent Title: Phosphine oxide alkyl amide substituted heteroaryl compounds as modulators of IL-12, IL-23 and/or IFN alpha responses
-
Application No.: US15838434Application Date: 2017-12-12
-
Publication No.: US10294256B2Publication Date: 2019-05-21
- Inventor: Michael G. Yang , Zili Xiao , John V. Duncia , David S. Weinstein
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- Main IPC: C07D401/00
- IPC: C07D401/00 ; C07F9/6558 ; A61P29/00 ; A61P37/00 ; C07F9/6509 ; A61K31/50 ; A61K31/501 ; C07D401/12 ; C07D237/24
Abstract:
Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where all substituents are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.
Public/Granted literature
Information query
