System and method embodiments are provided for enabling software defined topology (SDT) to interwork with network function virtualization (NFV) and software defined networking (SDN). In an embodiment, a method for software defined topology (SDT) management interworking with network function virtualization (NFV) and software defined networking (SDN) includes receiving, at an SDT Manager, from a service customer, a service request comprising a virtual service function forwarding graph (VSF FG); selecting a virtual network function (VNF) forwarding graph (FG) template in accordance with the received service request; generating a virtual function (VF) FG in accordance with the service request and the selected VNF FG template; selecting a point of presence (PoPs) for a VF in the VF FG; and transmitting, to an NFV Manager, instructions to instantiate the VF in accordance with at least one of the generated VF FG and the determined PoP.