Invention Grant
- Patent Title: Proton pump inhibitors
-
Application No.: US14450191Application Date: 2014-08-01
-
Publication No.: US10308605B2Publication Date: 2019-06-04
- Inventor: Masahiro Kajino , Atsushi Hasuoka , Naoki Tarui , Terufumi Takagi
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent David G. Conlin; Joohee Lee
- Priority: JP2004-289169 20040930; JP2005-044740 20050221
- Main IPC: C07D207/48
- IPC: C07D207/48 ; C07D409/04 ; C07D401/12 ; C07D403/12 ; C07D417/12 ; C07D401/04 ; C07D405/12 ; A61K31/4439 ; A61K31/4025 ; A61K31/41 ; A61K31/501 ; A61K31/506 ; C07D207/335 ; C07D403/04 ; C07D405/04 ; C07D409/12 ; C07D487/04

Abstract:
A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R1is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R2, R3 and R4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R5 and R6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof, or a prodrug thereof is provided.
Public/Granted literature
- US20140343070A1 PROTON PUMP INHIBITORS Public/Granted day:2014-11-20
Information query