Medical devices performing diagnostic and/or treatment procedures, such as retrieving autogenous materials and/or foreign materials from a patient are disclosed. The medical device may comprise a handle, a shaft coupled to the handle, and a retrieval device movably disposed within a working channel of the shaft. The handle may include a steering mechanism for deflecting a deflect a distal end of the shaft and a control mechanism for translating the retrieval device within the working channel. The retrieval device may be integrated into the medical device.