- 专利标题: Bicyclic derivatives, a process for their preparation and pharmaceutical compositions containing them
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申请号: US15738186申请日: 2016-06-22
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公开(公告)号: US10323041B2公开(公告)日: 2019-06-18
- 发明人: Balazs Balint , Márton Csékei , Zoltán Szabó , Zoltan Szlavik , András Kotschy , Maïa Chanrion , Olivier Geneste , I-Jen Chen , James Edward Paul Davidson , James Brooke Murray , Szabolcs Sipos , Levente Ondi , Ágnes Proszenyák
- 申请人: LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD
- 申请人地址: FR Suresnes GB Winnersh Berkshire
- 专利权人: LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人: LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人地址: FR Suresnes GB Winnersh Berkshire
- 代理机构: Hueschen and Sage
- 优先权: FR1555750 20150623
- 国际申请: PCT/EP2016/064418 WO 20160622
- 国际公布: WO2016/207217 WO 20161229
- 主分类号: C07D491/048
- IPC分类号: C07D491/048 ; A61K31/519 ; C07D495/04 ; C07D403/12 ; C07D333/56 ; C07D405/04 ; C07D405/12 ; C07D409/12 ; C07D471/04 ; C07D487/04 ; C07D491/04 ; C07D209/12 ; C07D307/80 ; C07D307/81 ; A61P35/02 ; A61K45/06
摘要:
Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A and n are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.
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