Invention Grant
- Patent Title: Indole carboxamide compounds
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Application No.: US15886192Application Date: 2018-02-01
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Publication No.: US10329274B2Publication Date: 2019-06-25
- Inventor: Qingjie Liu , Scott Hunter Watterson , John E. Macor , Khehyong Ngu , Saleem Ahmad
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Gary Greenblatt
- Main IPC: A01N57/26
- IPC: A01N57/26 ; A61K31/66 ; A01N43/00 ; A61K31/397 ; C07D401/10 ; A61P29/00 ; C07D403/12 ; C07D209/08 ; C07D209/18 ; C07D487/10 ; C07D487/04 ; C07D471/04 ; C07D417/04 ; C07D413/04 ; C07D403/10 ; C07D403/04 ; C07D401/12 ; C07D401/06 ; C07D401/04 ; A61P37/00

Abstract:
Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Public/Granted literature
- US20190119245A1 INDOLE CARBOXAMIDE COMPOUNDS Public/Granted day:2019-04-25
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