Invention Grant
- Patent Title: Antibodies to VLA-1
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Application No.: US15470442Application Date: 2017-03-27
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Publication No.: US10336826B2Publication Date: 2019-07-02
- Inventor: Michael Karpusas , Paul D. Lyne , Ellen A. Garber Stark , Jose William Saldanha
- Applicant: BIOGEN MA INC.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Jonathan M. Sparks; Marcie B. Clarke
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K39/00
Abstract:
Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.
Public/Granted literature
- US20170335000A1 ANTIBODIES TO VLA-1 Public/Granted day:2017-11-23
Information query
