This disclosure describes systems, methods, and devices related to reverse direction multi-user multiple input multiple output (MU-MIMO). A device may determine a reverse direction indication to be included in a frame for transmission to one or more first devices in a MU-MIMO communication. The device may cause to wirelessly transmit the frame to a first device of the one or more first devices. The device may identify an acknowledgment frame from the at least one of the first devices based at least in part on the reverse direction indication