Methods, apparatus, systems and articles of manufacture to map a set of instructions onto a data flow graph are disclosed herein. An example apparatus includes a variable handler to modify a variable in the set of instructions. The variable is used multiple times in the set of instructions and the set of instructions are in a static single assignment form. The apparatus also includes a PHI handler to replace a PHI instruction contained in the set of instructions with a set of control data flow instructions and a data flow graph generator to map the set of instructions modified by the variable handler and the PHI handler onto a data flow graph without transforming the instructions out of the static single assignment form.