Invention Grant
- Patent Title: Materials and methods for improving lung function and for prevention and/or treatment of radiation-induced lung complications
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Application No.: US14773960Application Date: 2014-03-11
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Publication No.: US10350185B2Publication Date: 2019-07-16
- Inventor: Sadasivan Vidyasagar , Paul Okunieff
- Applicant: University of Florida Research Foundation, Inc.
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee Address: US FL Gainesville
- Agency: Greenberg Traurig, LLP
- International Application: PCT/US2014/023363 WO 20140311
- International Announcement: WO2014/164736 WO 20141009
- Main IPC: A61K33/14
- IPC: A61K33/14 ; A61K9/00 ; A61K31/198 ; A61K31/405
Abstract:
The subject invention provides therapeutic compositions and uses thereof for improving pulmonary function. In one embodiment, the therapeutic composition comprises one or more free amino acids selected from lysine, glycine, threonine, valine, tyrosine, aspartic acid, isoleucine, tryptophan, asparagine, and serine; and electrolytes. In one embodiment, the subject invention can be used to prevent or treat long-term lung complications induced by radiation.
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