- 专利标题: Small molecule inhibitors of influenza A RNA-dependent RNA polymerase
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申请号: US16110634申请日: 2018-08-23
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公开(公告)号: US10350225B1公开(公告)日: 2019-07-16
- 发明人: Kayvan Niazi , Shahrooz Rabizadeh , Anne-Laure Le Ny , Oleksandr Buzko , Justin Golovato , Patrick Soon-Shiong
- 申请人: Nant Holdings IP, LLC
- 申请人地址: US CA Culver City
- 专利权人: Nant Holdings IP, LLC
- 当前专利权人: Nant Holdings IP, LLC
- 当前专利权人地址: US CA Culver City
- 代理机构: Lucas & Mercanti, LLP
- 主分类号: C07D417/12
- IPC分类号: C07D417/12 ; A61K31/635 ; A61K31/55 ; A61K31/501 ; A61K31/5377 ; A61K31/47 ; A61K31/4409 ; A61K31/4709 ; A61K31/496 ; A61K31/4545 ; A61K31/444 ; A61K31/426 ; A61K31/454 ; G16B5/00
摘要:
Compositions, compounds, and methods with significant antiviral effect against RNA viruses and especially orthomyxoviruses are contemplated, and target the viral promoter that is formed by the 5′ and 3′-UTR sequences of the viral genome.
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