Invention Grant
- Patent Title: Factor IXa inhibitors
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Application No.: US15550862Application Date: 2016-02-12
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Publication No.: US10351558B2Publication Date: 2019-07-16
- Inventor: Dongfang Meng , Hong Li , Meng Yang , Manuel de Lera Ruiz , Sunita V. Dewnani , Tianying Jian , Dann L. Parker, Jr. , Ting Zhang , Louis-Charles Campeau , Harold B. Wood , Jiayi Xu , Richard Berger , Jane Yang Wu , Robert K. Orr , Shawn P. Walsh , Bart Harper
- Applicant: Merck Sharp & Dohme Corp. , Dongfang Meng , Hong Li , Meng Yang , Manuel de Lera Ruiz , Sunita V. Dewnani , Tianying Jian , Dann L. Parker, Jr. , Ting Zhang , Louis-Charles Campeau , Harold B. Wood , Jiayi Xu , Richard Berger , Jane Yang Wu , Robert K. Orr , Shawn P. Walsh , Bart Harper
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; John C. Todaro
- International Application: PCT/US2016/017652 WO 20160212
- International Announcement: WO2016/133793 WO 20160825
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D403/12 ; C07D417/14 ; A61P9/00 ; C07D413/14 ; C07D471/14 ; C07D498/04 ; C07D513/04
Abstract:
The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.
Public/Granted literature
- US20180022747A1 Factor IXa Inhibitors Public/Granted day:2018-01-25
Information query
